CDC34抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CDC34抗体

CDC34抗体

商家询价

产品名称： CDC34抗体

英文名称： CDC34Antibody

产品编号： XY10964-2

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CDC34抗体

Applications
In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 10964-2-AP;human pancreas tissuehuman pancreas tissue were subjected to SDS PAGE followed by western blot with 10964-2-AP(CDC34 antibody) at dilution of 1:300
  • 10964-2-AP;human prostate cancerImmunohistochemical of paraffin-embedded human prostate cancer using 10964-2-AP(CDC34 antibody) at dilution of 1:100 (under 10x lens)
  • 10964-2-AP;mouse testis tissueIP Result of anti-CDC34 (IP:10964-2-AP, 4ug; Detection:10964-2-AP 1:500) with mouse testis tissue lysate 4000ug.
Positive WB detected in Human pancreas tissue, human brain tissue
Positive IP detected in Mouse testis tissue
Positive IHC detected in Human prostate cancer tissue
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:2000
IHC : 1:20-1:200
 CDC34抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CDC34 fusion protein ag1438 Full name Cell division cycle 34 homolog (S. cerevisiae)
Calculated molecular
weight		 34 kDa Observed molecular 
weight		 34 kDa
GenBank accession 
number		 BC009850 Gene ID (NCBI) 997
Gene symbol CDC34 Synonyms CDC34, E2 CDC34, UBC3, UBCH3, UBE2R1, Ubiquitin protein ligase R1
Background CDC34抗体

CDC34 is also named as UBCH3, UBE2R1(Ubiquitin-conjugating enzyme E2 R1) and belongs to the ubiquitin-conjugating enzyme family. Cdc34 enzyme is itself a substrate for the type of polyubiquitin modification that is known to cause targeting of proteins for degradation. It is phosphorylated in vivo, providing yet another potential means for control of its activity. And the predominantly nuclear localization of this enzyme suggests that substrate molecules relevant to its cell cycle function are similarly located within the nucleus(PMID:8164658). Human CDC34 could substitute efficiently for yeast CDC34(PMID:8248134). It can form a homodimer(PMID:8383676). CDC34抗体

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