FITC标记的EFCAB7蛋白抗体
产品名称： FITC标记的EFCAB7蛋白抗体
英文名称： Anti-EFCAB7/FITC
产品编号： HZ-14515R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EFCAB7/FITC Conjugated antibody
FITC标记的EFCAB7蛋白抗体
| 英文名称 | Anti-EFCAB7/FITC |
| 中文名称 | FITC标记的EFCAB7蛋白抗体 |
| 别 名 | EF hand calcium binding domain 7; EF-hand calcium-binding domain-containing protein 7; Efcab7; EFCB7_HUMAN; KIAA1799; RP4-534K7.1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 72kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EFCAB7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. Similarity: Contains 3 EF-hand domains. Database links: Entrez Gene: 84455 Human Entrez Gene: 230500 Mouse Entrez Gene: 362549 Rat SwissProt: A8K855 Human SwissProt: Q8VDY4 Mouse Unigene: 652324 Human Unigene: 331727 Mouse Unigene: 162071 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
第1号染色体是最大的人类染色体，跨越2亿6000万个碱基对，占人类基因组的8%。有1号染色体上约3000个基因，并结合大量的基因也有大量的与1号染色体相关的疾病。值得注意的是，罕见病早衰与老化Hutchinson Gilford编码lamin A.当缺陷的LMNA基因相关，LMNA基因产物可以建立在原子核的特性及其产生原因核泡。迅速增强衰老的机制尚不清楚，是一个继续探索的话题。MutyH基因位于1号染色体上，是家族性腺瘤性息肉病的部分原因。Stutkle综合征、帕金森病、高雪氏病和Aukes综合征也与1号染色体有关。在1q中发现了一个断点，它破坏了DISC1基因并与精神分裂症联系在一起。在1号染色体畸变在多种癌症包括头颈部癌，恶性黑色素瘤和多发性骨髓瘤。